clinical research

Prognosis of the endodontic treatment according to the apical periodontitis lesion size: a case-control study

Liliana Artaza, PhD 1,2

Andrea F. Campello, PhD 3

Giuliana Soimu, MS 1

Danielle D. Voigt, PhD 1

Flávio R. F. Alves, PhD 1,3

José F. Siqueira Jr, PhD 1,3

Isabela N. Rôças, PhD 1,3

https://doi.org/10.71347/kgn741cz


1 Department of Endodontics, Grande Rio University (UNIGRANRIO), Rio de Janeiro, RJ, Brazil.

2 Department of Endodontics, Maimonides University (UMAI), Buenos Aires, Argentina.

3 Department of Endodontics and Dental Research, Iguaçu University (UNIG), Nova Iguaçu, RJ, Brazil.


Corresponding author:

Flávio R. F. Alves

Department of Endodontics and Dental Research

Av. Abílio Augusto Távora, 2134

Nova Iguaçu – RJ

Brazil 26260-045

e-mail: flavioferreiraalves@gmail.com


Key words: apical periodontitis; root canal treatment; outcome; case-control study

Acknowledgements: This study was supported by grants from Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ) and Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq), Brazilian Governmental Institutions.

The authors deny any conflicts of interest.

Abstract


Objective This case-control study compared the outcome of the nonsurgical root canal treatment/retreatment of teeth with small and large apical periodontitis lesions. Other factors associated with the outcome of the treatment of teeth with apical periodontitis were also assessed.

Methods Ninety-six patients (48 cases and 48 controls) were selected from 240 treated teeth from 206 individuals, and paired for age and tooth type. An experienced operator treated all teeth over a period of 23 years. Cases were treated/retreated using irrigation with 2.5% sodium hypochlorite. The clinical and radiographic outcome was classified as healed, healing or diseased. Healed cases were considered as success and diseased cases were considered as failures. Healing cases consisted of teeth with lesions that decreased in size and were regarded as failure in a rigid criterion or as success in a lenient criterion.

Results Overall, 62.5% of the cases were classified as healed, 28% as healing, and 9% as diseased. In the lenient criterion, the success rates in teeth with small and large lesions were 91.7% and 89.6%, respectively (P > .05). In the rigid criterion, the success rate was the same for both conditions (62.5%). Logistic regression analysis showed that history of a previous abscess significantly affected the outcome (P < .05).

Conclusions The size of apical periodontitis lesion did not impact the outcome of the endodontic treatment when performed by the same experienced operator.


Introduction


Apical periodontitis is caused by bacterial infection of the root canal system (Sundqvist 1976). This disease is characterized by an inflammatory response to bacteria leaving the canal via apical and lateral foramina and typically results in bone resorption around the root apex.

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references

Amaral RR, Braga T, Siqueira JF, Jr. et al. (2022) Root canal microbiome associated with asymptomatic apical periodontitis as determined by high-throughput sequencing. Journal of Endodontics 48, 487-95.

Artaza L, Campello AF, Soimu G, Alves FRF, Rocas IN, Siqueira JF, Jr. (2021) Clinical and radiographic outcome of the root canal treatment of infected teeth with associated sinus tract: A retrospective study. Australian Endodontic Journal 47, 599-607.

Artaza L, Campello AF, Soimu G, Alves FRF, Rocas IN, Siqueira JF, Jr. (2024) Outcome of Nonsurgical Root Canal Treatment of Teeth With Large Apical Periodontitis Lesions: A Retrospective Study. Journal of Endodontics.

Azim AA, Griggs JA, Huang GT (2016) The Tennessee study: factors affecting treatment outcome and healing time following nonsurgical root canal treatment. International Endodontic Journal 49, 6-16.

Baseri M, Radmand F, Milani AS, Gavgani LF, Salehnia F, Dianat O (2023) The effect of periapical lesion size on the success rate of different endodontic treatments: a systematic review and meta-analysis. Evid Based Dent 24, 43.

Byström A, Happonen RP, Sjogren U, Sundqvist G (1987) Healing of periapical lesions of pulpless teeth after endodontic treatment with controlled asepsis. Endodontics and Dental Traumatology 3, 58-63.

Farzaneh M, Abitbol S, Friedman S (2004) Treatment outcome in endodontics: the Toronto study. Phases I and II: Orthograde retreatment. Journal of Endodontics 30, 627-33.

Friedman S (2017) Prognosis of healing in treated teeth with endodontic infections. In AF Fouad ed. Endodontic microbiology, 2nd edn edn; pp. 341-84. Hoboken, NJ: Wiley & Sons.

Friedman S, Lost C, Zarrabian M, Trope M (1995) Evaluation of success and failure after endodontic therapy using a glass ionomer cement sealer. Journal of Endodontics 21, 384-90.

Gulabivala K, Ng YL (2023) Factors that affect the outcomes of root canal treatment and retreatment-A reframing of the principles. International Endodontic Journal 56 Suppl 2, 82-115.

Hoskinson SE, Ng YL, Hoskinson AE, Moles DR, Gulabivala K (2002) A retrospective comparison of outcome of root canal treatment using two different protocols. Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology 93, 705-15.

Lin LM, Ricucci D, Lin J, Rosenberg PA (2009) Nonsurgical root canal therapy of large cyst-like inflammatory periapical lesions and inflammatory apical cysts. Journal of Endodontics 35, 607-15.

Nair PN (1998) New perspectives on radicular cysts: do they heal? International Endodontic Journal 31, 155-60.

Ng YL, Mann V, Gulabivala K (2011) A prospective study of the factors affecting outcomes of nonsurgical root canal treatment: part 1: periapical health. International Endodontic Journal 44, 583-609.

Orstavik D, Kerekes K, Eriksen HM (1986) The periapical index: a scoring system for radiographic assessment of apical periodontitis. Endodontics and Dental Traumatology 2, 20-34.

Patel S, Brown J, Semper M, Abella F, Mannocci F (2019) European Society of Endodontology position statement: Use of cone beam computed tomography in Endodontics: European Society of Endodontology (ESE) developed by. International Endodontic Journal 52, 1675-8.

Peters LB, Wesselink PR (2002) Periapical healing of endodontically treated teeth in one and two visits obturated in the presence or absence of detectable microorganisms. International Endodontic Journal 35, 660-7.

Ricucci D, Rôças IN, Hernandez S, Siqueira JF, Jr. (2020) "True" versus "bay" apical cysts: clinical, radiographic, histopathologic, and histobacteriologic features. Journal of Endodontics 46, 1217-27.

Ricucci D, Siqueira JF, Jr. (2010) Biofilms and apical periodontitis: study of prevalence and association with clinical and histopathologic findings. Journal of Endodontics 36, 1277-88.

Ricucci D, Siqueira JF, Jr., Lopes WS, Vieira AR, Rôças IN (2015) Extraradicular infection as the cause of persistent symptoms: a case series. Journal of Endodontics 41, 265-73.

Siqueira JF, Jr, Rôças IN, Paiva SSM, Magalhães KM, Guimarães-Pinto T (2007) Cultivable bacteria in infected root canals as identified by 16S rRNA gene sequencing. Oral Microbiology and Immunology 22, 266-71.

Siqueira JF, Jr., Rôças IN (2008) Clinical implications and microbiology of bacterial persistence after treatment procedures. Journal of Endodontics 34, 1291-301 e3.

Sjögren U, Hagglund B, Sundqvist G, Wing K (1990) Factors affecting the long-term results of endodontic treatment. Journal of Endodontics 16, 498-504.

Strindberg LZ (1956) The dependence of the results of pulp therapy on certain factors. Acta Odontologica Scandinavica 14 (suppl 21), 1-175.

Sundqvist G (1976) Bacteriological studies of necrotic dental pulps [Odontological Dissertation no.7]. Umea, Sweden: University of Umea.

Weiger R, Rosendahl R, Lost C (2000) Influence of calcium hydroxide intracanal dressings on the prognosis of teeth with endodontically induced periapical lesions. International Endodontic Journal 33, 219-26.

Zhang MM, Fang GF, Chen XT, Liang YH (2021) Four-year Outcome of Nonsurgical Root Canal Retreatment Using Cone-beam Computed Tomography: A Prospective Cohort Study. Journal of Endodontics 47, 382-90.