ISSN: 3059-6254
Endo Sapiens Journal
Scientific journal on research in endodontics by Domenico Ricucci & José Siqueira
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Scientific journal on research in endodontics (by Domenico Ricucci & José Siqueira)
Endo Sapiens Journal is an international, peer-reviewed, scientific journal in endodontics driven by Dr. Domenico Ricucci and Dr. José Siqueira. The access requires registration free of charge.
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The main features of Endo Sapiens Journal
Peer-reviewed scientific journal in endodontics driven by Domenico Ricucci and José Siqueira
  • Latest database of scientific research in endodontics
    Endo Sapiens Journal is a database of the most recent scientific research in modern endodontics
  • Free of charge access
    The access to the Journal is free of charge. It just requires an easy registration to enter your personal account and that's it!
  • Scientifically driven by Dr. Domenico Ricucci and Dr. José Siqueira
    The Endo Sapiens Journal is scientifically driven by two foremost researchers in modern endodontics - Dr. Domenico Ricucci and Dr. José Siqueira
Latest articles (2025)
Extraosseous inflammatory lesion of endodontic origin in a mandibular premolar with failing root canal treatment. A case report
By Domenico Ricucci, Simona Loghin, Stephen Smith, Craig S. Schneider, Isabela N. Rôças, José F. Siqueira Jr
https://doi.org/10.71347/cghr45d6
Abstract
Background: This article reports on a case of extraosseous inflammatory lesion of endodontic origin (EILEO) that was recalcitrant to nonsurgical root canal treatment and was caused by a complex intraradicular and extraradicular bacterial infection.
Case description: The histopathological and histobacteriological aspects of the biopsy specimen were evaluated. The affected tooth was a mandibular premolar that exhibited an abraded crown with exposed dentin and enamel cracks, but no caries. The patient reported previous abscess episodes and presented with symptoms and a sinus tract. Nonsurgical root canal treatment was not effective in controlling infection, even after using ultrasonic agitation of irrigants and intracanal medication.

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Filling material extrusion into maxillary sinus causing severe pain: resolution via laparoscopic surgery
By Márcia Franzoni, Fátima G. Bueno-Camilo, Flávio R. F. Alves, José F. Siqueira Jr, Isabela N. Rôças
https://doi.org/10.71347/esj42dh78
Abstract
Background: Given the anatomical proximity, pathologic conditions and endodontic treatment procedures in maxillary posterior teeth may affect the maxillary sinus.
Case description: This report describes a case of large extrusion of filling material to the maxillary sinus, resulting in persistent acute pain and requiring hospitalization and surgical removal of the material via videolaparoscopy. A 34-year-old female experienced persistent pain in the left upper posterior region of the face, three months after endodontic treatment of tooth 14.

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Biological and procedural factors affecting the outcome of apical microsurgery. A case report
By Domenico Ricucci, Ya-Hsin Yu, Samuel Kratchman, Irina Milovidova, Isabela N. Rôças, José F. Siqueira Jr
https://doi.org/10.71347/dhf874kg1
Abstract
Background: The success rate of contemporary apical surgery is high after the introduction of magnification, ultrasonics, and bioceramic materials. Persistent apical periodontitis following surgical treatment is usually related to the failure in eliminating or at least sealing residual bacteria occurring in the root canal system.
Case Description: This article reports on a clinical case of postsurgical apical periodontitis associated with a mandibular molar exhibiting failing root-end filling with a bioceramic (calcium silicate-based) material. The tooth had been subjected to retreatment and later to apical surgery because of persistent apical periodontitis. After a period in that the lesions had apparently healed based on radiographs, the appearance of a sinus tract and the observation of recurrence of the apical periodontitis lesions on both roots as shown by CBCT led to indication for a new surgery.

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Misdiagnosis of “J-shaped” or “halo” endodontic lesions influence treatment planning among non-endodontist practitioners
By Jorge Vera, Carolina Saucedo, Ana Arias, Felipe Restrepo, Paula Villa, Monica Romero, Jorge Ochoa, Rubén Rosas
https://doi.org/10.71347/yjfd356fd
Abstract
Objective: Radiographic “J-shaped” lesions can be present in teeth without vertical root fractures (VRF). The objective of this study was to assess the recommended treatment plan in this type of case.
Methods: Radiographs and clinical data from fifteen necrotic or endodontically-treated teeth with radiographic/tomographic “J-shaped” or “halo” endodontic lesions were presented during a lecture to 323 evaluators for treatment selection. The selection of treatments (endodontic therapy, periodontal therapy, endo-perio combined treatment or extraction) and the influence of patient/tooth-related factors in treatment decision planning were statistically compared.

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Prognosis of the endodontic treatment according to the apical periodontitis lesion size: a case-control study
By Liliana Artaza, Andrea F. Campello, Giuliana Soimu, Danielle D. Voigt, Flávio R. F. Alves, José F. Siqueira Jr, Isabela N. Rôças
https://doi.org/10.71347/kgn741cz
Abstract
Objective. This case-control study compared the outcome of the nonsurgical root canal treatment/retreatment of teeth with small and large apical periodontitis lesions. Other factors associated with the outcome of the treatment of teeth with apical periodontitis were also assessed.
Methods. Ninety-six patients (48 cases and 48 controls) were selected from 240 treated teeth from 206 individuals, and paired for age and tooth type. An experienced operator treated all teeth over a period of 23 years. Cases were treated/retreated in a single visit using irrigation with 2.5% sodium hypochlorite. The clinical and radiographic outcome was classified as healed, healing or diseased. Healed cases were considered as success and diseased cases were considered as failures. Healing cases consisted of teeth with lesions that decreased in size and were regarded as failure in a rigid criterion or as success in a lenient criterion.

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